Work by Professor Michael Roe of North Carolina University, USA, showed that Wild Tomato Extract (IBI-246) is so effective at repelling insects that the University patented the substance. Clinical trials under Professor Daniel Sonenshine showed that Natural Wild Tomato Extract produced by Santecare, Italy, repelled Aedes mosquito for 12 hours, DEET for 10 hours and Citronella less than 3 hours. It is highly safe for the whole family while DEET is dangerous with improper use especially children.